This course will develop an understanding of the basic properties of cells and organelles, integrating principles of cell structure and function with the underlying molecular mechanisms such as signal transduction and cell regulation. In addition, students will examine properties of differentiated cell systems and tissue. Discussions will focus on aspects of gene regulation, genomics, cell cycle control, protein synthesis, intracellular protein trafficking and protein degradation in eukaryotic cells. These concepts will be discussed in the context of how defects in cellular processes give rise to disease. Students will be introduced to scientific literature, in particular how to critically examine & interpret data.